ChatDysBETA
Sign In
← All ConditionsShare on X
🫀

Dysautonomia / Autonomic Nervous System Disorders

When the autonomic nervous system fails to regulate properly

Dysautonomia is an umbrella term for conditions affecting the autonomic nervous system (ANS), which controls involuntary functions like heart rate, blood pressure, digestion, and temperature regulation. It affects an estimated 70 million people worldwide.

Types & Subtypes

POTS (Postural Orthostatic Tachycardia Syndrome)

Heart rate increases by ≥30 bpm within 10 minutes of standing

NCS (Neurocardiogenic Syncope)

Fainting caused by a sudden drop in heart rate and blood pressure

IST (Inappropriate Sinus Tachycardia)

Resting heart rate consistently above 100 bpm without cause

OH (Orthostatic Hypotension)

Blood pressure drops significantly when standing

MSA (Multiple System Atrophy)

Progressive neurological disorder affecting the ANS

Common Symptoms

Rapid heartbeat on standingDizziness/lightheadednessFainting or near-faintingBrain fogFatigueNauseaTemperature dysregulationExercise intoleranceHeadachesChest pain

Management & Treatment Options

Increased salt and fluid intake
Compression garments
Beta-blockers
Fludrocortisone
Midodrine
Ivabradine
Graded exercise therapy
Elevation of head of bed

⚠️ Always consult a healthcare provider before starting any treatment.

Trusted Resources

🔗 Dysautonomia International🔗 Standing Up to POTS🔗 The Dysautonomia Project

Knowledge Base

6 documents

Sourced from authoritative medical organizations and peer-reviewed research.

🧬

Genetic Variants

GWAS Research
See all variants →

Top genetic variants associated with Dysautonomia in published genome-wide association studies.

rs1800497

ANKK1

Dopamine signaling

OR 1.28

p=3.4e-7

rs4961

ADD1

Blood pressure regulation

OR 1.22

p=5.6e-7

rs699

AGT

Renin-angiotensin system

OR 1.19

p=8.2e-7

⚠️ Genetic associations do not determine diagnosis. Consult a genetic counselor.

Upload 23andMe →

Have questions about Dysautonomia?

Ask our AI assistant trained on the latest medical research.

Ask ChatDys AIJoin the Forum